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Spotlight on Apoptosis
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Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies
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1
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AM Senderowicz
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| Abstract Full Article PDF
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Editorial
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Hypothesis: Phenol and hydroquinone derived mainly from diet and gastrointestinal flora activity are causal factors in leukemia
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10
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TA McDonald, NT Holland, C Skibola, P Duramad & MT Smith
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| Abstract Full Article PDF
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Reviews
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Molecular signals in anti-apoptotic survival pathways
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21
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DM O'Gorman & TG Cotter
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| Abstract Full Article PDF
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Chronic neutrophilic leukemia (CNL): a clinical, pathologic and cytogenetic study
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35
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MA Elliott, GW Dewald, A Tefferi & CA Hanson
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| Abstract Full Article PDF
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Original Manuscripts
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Second malignancy after treatment of childhood acute myeloid leukemia
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41
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W Leung, RC Ribeiro, M Hudson, X Tong, DK Srivastava, JE Rubnitz, JT Sandlund, BI Razzouk, WE Evans & C-H Pui
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| Abstract Full Article PDF
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Extramedullary infiltrates at diagnosis have no prognostic significance in children with acute myeloid leukaemia
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46
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MM Bisschop, T Révész, M Bierings, JF van Weerden, ER van Wering, K Hählen & A van der Does-van den Berg
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| Abstract Full Article PDF
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Purified autologous grafting in childhood acute lymphoblastic leukemia in second remission: evidence for long-term clinical and molecular remissions
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50
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A Balduzzi, G Gaipa, S Bonanomi, M Dassi, P Perseghin, F Buscemi, E D'Aniello, A Rovelli, R Schirò, D Longoni, A Rambaldi, C Uderzo & A Biondi
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| Abstract Full Article PDF
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Comparison of outcome in acute myelogenous leukemia patients with translocation (8;21) found by standard cytogenetic analysis and patients with AML1/ETO fusion transcript found only by PCR testing
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57
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JE Sarriera, M Albitar, Z Estrov, C Gidel, R Aboul-Nasr, T Manshouri, S Kornblau, K-S Chang, H Kantarjian & E Estey
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| Abstract Full Article PDF
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Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia
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62
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A Krämer, H Löffler, J Bergmann, A Hochhaus & R Hehlmann
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| Abstract Full Article PDF
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Modulation of ara-CTP levels by fludarabine and hydroxyurea in leukemic cells
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69
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M Ahlmann, C Lanvers, K Lümkemann, C Rössig, A Freund, M Baumann & J Boos
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| Abstract Full Article PDF
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6-Mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia
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74
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K Schmiegelow & U Bretton-Meyer
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| Abstract Full Article PDF
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Cyclosporin increases cellular idarubicin and idarubicinol concentrations in relapsed or refractory AML mainly due to reduced systemic clearance
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80
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M Smeets, R Raymakers, P Muus, G Vierwinden, P Linssen, R Masereeuw & T de Witte
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| Abstract Full Article PDF
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Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation
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89
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I Kitabayashi, Y Aikawa, A Yokoyama, F Hosoda, M Nagai, N Kakazu, T Abe & M Ohki
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| Abstract Full Article PDF
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Detection of E2A translocations in leukemias via fluorescence in situ hybridization
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95
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T Boomer, M Varella-Garcia, L McGavran, L Meltesen, AS Olsen & SP Hunger
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| Abstract Full Article PDF
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C/EBP -/- mice: increased rate of myeloid proliferation and apoptosis
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103
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W Verbeek, M Wächter, J Lekstrom-Himes & HP Koeffler
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| Abstract Full Article PDF
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The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro
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112
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S Horn, J Meyer, J Heukeshoven, B Fehse, C Schulze, S Li, J Frey, S Poll, C Stocking & M Jücker
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| Abstract Full Article PDF
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Immunoglobulin lambda isotype gene rearrangements in B cell malignancies
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121
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T Tümkaya, M van der Burg, R Garcia Sanz, M Gonzalez Diaz, AW Langerak, JF San Miguel & JJM van Dongen
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| Abstract Full Article PDF
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HLA class I antigen cell surface expression is preserved on acute myeloid leukemia blasts at diagnosis and at relapse
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128
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M Wetzler, MR Baer, SJ Stewart, K Donohue, L Ford, CC Stewart, EA Repasky & S Ferrone
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| Abstract Full Article PDF
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Quantification of minimal residual disease in children with oligoclonal B-precursor acute lymphoblastic leukemia indicates that the clones that grow out during relapse already have the slowest rate of reduction during induction therapy
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134
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V de Haas, OJHM Verhagen, AEGKr von dem Borne, W Kroes, H van den Berg & CE van der Schoot
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| Abstract Full Article PDF
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Development and characterization of T cell leukemia cell lines established from SCL/LMO1 double transgenic mice
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141
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DS Chervinsky, DH Lam, X-F Zhao, MP Melman & PD Aplan
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| Abstract Full Article PDF
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Establishment of a follicular lymphoma cell line (FLK-1) dependent on follicular dendritic cell-like cell line HK
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148
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Y Kagami, J Jung, YS Choi, K Osumi, S Nakamura, Y Morishima & M Seto
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| Abstract Full Article PDF
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Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia
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157
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T Uchida, T Kinoshita, T Ohno, H Ohashi, H Nagai & H Saito
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| Abstract Full Article PDF
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Bio-technical Methods Section (BTS)
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Quantification of minimal residual disease in T-lineage acute lymphoblastic leukemia with the TAL-1 deletion using a standardized real-time PCR assay
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166
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X Chen, Q Pan, P Stow, FG Behm, R Goorha, C-H Pui & GAM Neale
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| Abstract Full Article PDF
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Angiogenesis in multiple myeloma: correlation between in vitro endothelial colonies growth (CFU-En) and clinical–biological features
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171
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M Dominici, D Campioni, F Lanza, M Luppi, P Barozzi, S Pauli, R Milani, F Cavazzini, M Punturieri, R Trovato, G Torelli & G Castoldi
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| Abstract Full Article PDF
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Detection of secondary genetic aberrations in follicle center cell derived lymphomas: assessment of the reliability of comparative genomic hybridization and standard chromosome analysis
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177
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A Viardot, JI Martin-Subero, R Siebert, S Harder, S Gesk, M Bentz & B Schlegelberger
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| Abstract Full Article PDF
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Correspondence
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The natural history and clinico-pathological features of the variant form of hairy cell leukemia
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184
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E Matutes, A Wotherspoon, V Brito-Babapulle & D Catovsky
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Severe thrombocytopenia and clinical bleeding associated with rituximab infusion in a lymphoma patient with massive splenomegaly without leukemic invasion
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186
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C Rigamonti, C Volta, S Colombi, L Forti, F Savinelli, G Gaidano & E Bartoli
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Remission of severe cold agglutinin disease Rituximab therapy
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187
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N Layios, E Van Den Neste, E Jost, V Deneys, JM Scheiff & A Ferrant
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Age cohort subgroups in adult acute myeloid leukaemia studies - the population perspective
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188
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SJ Proctor & PRA Taylor
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CD13/aminopeptidase N involvement in dendritic cell maturation
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190
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VHJ van der Velden, PJM Leenen & HA Drexhage
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Deletion of the multidrug resistance protein 1 (MRP1) gene in acute myeloid leukemia patients with inversion 16: expression of MRP1 homologues
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191
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DM van der Kolk, EGE de Vries & E Vellenga
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| Full Article PDF
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Is HLA-DR4 or the HLA-DRB1*0402 allele associated with decreased risk for CML?
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192
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G Pawelec & W Wagner
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