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Leukemia
December 2000, Volume 14, Issue 12
Table of Contents
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Leukemia
Editorial

Spotlight on Apoptosis

Review and Meeting Report

Original Manuscripts

Bio-Technical Methods Section (BTS)

Spotlight on Long-Term Results of Pediatric ALL Clinical Trials from 12 Study Groups World Wide

Original Manuscripts

Correspondence

Author Index

Keyword Index

Editorial
The dilemma of apoptosis in myelodysplasia and leukemia: a new promise of therapeutic intervention? 2017
MV Blagosklonny
Full Article    PDF

Spotlight on Apoptosis
Kinases: positive and negative regulators of apoptosis 2019
RA Franklin & JA McCubrey
Abstract    Full Article    PDF

Review and Meeting Report
Dissecting the pathways to death 2035
PT Daniel
Abstract    Full Article    PDF

Original Manuscripts
Expression and activity of caspases 1 and 3 in myelodysplastic syndromes 2045
D Boudard, O Sordet, C Vasselon, V Revol, M-F Berthéas, D Freyssenet, A Viallet, S Piselli, D Guyotat & L Campos
Abstract    Full Article    PDF
Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies 2052
A Mengarelli, AP Iori, C Guglielmi, MP Perrone, M Gozzer, C Girmenia, G Cimino, AM Testi, R Ricci, L De Felice, G Girelli, F Mandelli & W Arcese
Abstract    Full Article    PDF
Prognosis of patients with a second relapse of acute myeloid leukemia 2059
B Stoiser, P Knöbl, C Fonatsch, OA Haas, G Mitterbauer, A Weltermann, K Geissler, P Valent, W Sperr, I Pabinger, K Lechner & U Jaeger
Abstract    Full Article    PDF
Late autologous transplantation in chronic myelogenous leukemia with peripheral blood progenitor cells mobilized by G-CSF and interferon-alpha 2064
M Michallet, A Thiébaut, I Philip, C Charrin, C Vigouroux, X Thomas, K Bilger, A Belhabri, D Guyotat, B Corront, B Salles, C Dumontet, PY Péaud, JP Vilque, A Devidas & D Fière
Abstract    Full Article    PDF
Protean clinical manifestations in children with leukemias containing MLL-AF10 fusion 2070
L Gore, J Ess, MA Bitter, L McGavran, L Meltesen, Q Wei & SP Hunger
Abstract    Full Article    PDF
Disease- and treatment-related elevation of the neurodegenerative marker tau in children with hematological malignancies 2076
SW Van Gool, E Van Kerschaver, P Brock, H Pottel, F Hulstaert, E Vanmechelen, A Uyttebroeck, A Van De Voorde & H Vanderstichele
Abstract    Full Article    PDF
Phase I study of cinchonine, a multidrug resistance reversing agent, combined with the CHVP regimen in relapsed and refractory lymphoproliferative syndromes 2085
E Solary, L Mannone, D Moreau, D Caillot, R-O Casasnovas, H Guy, M Grandjean, J-E Wolf, F André, P Fenaux, P Canal, B Chauffert, A Wotawa, M Bayssas & P Genne
Abstract    Full Article    PDF
Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells 2095
FE Bertrand, CE Eckfeldt, AS Lysholm & TW LeBien
Abstract    Full Article    PDF
Fine characterization of childhood and adult acute lymphoblastic leukemia (ALL) by a proB and preB surrogate light chain-specific mAb and a proposal for a new B cell ALL classification 2103
B Lemmers, C Arnoulet, C Fossat, H Chambost, D Sainty, J Gabert & C Schiff
Abstract    Full Article    PDF
A transient dephosphorylation of JAK1 and JAK2 characterises the early-phase response of murine erythroleukemia cells to the differentiation inducer hexamethylenebisacetamide 2112
A Arcangeli, L Fontana, O Crociani, A Cherubini, G Hofmann, E Piccini, S Polvani, M D'Amico, M Carlà & M Olivotto
Abstract    Full Article    PDF
Modifications in phospholipase D activity and isoform expression occur upon maturation and differentiation in vivo and in vitro in human myeloid cells 2118
M El Marjou, V Montalescot, A Buzyn & B Geny
Abstract    Full Article    PDF
Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31 2128
H Xie, Z Hu, B Chyna, SK Horrigan & CA Westbrook
Abstract    Full Article    PDF
Proliferative status of primitive hematopoietic progenitors from patients with acute myelogenous leukemia (AML) 2135
Y Guan & DE Hogge
Abstract    Full Article    PDF
Genetic instability is associated with histological transformation of follicle center lymphoma 2142
M Nagy, M Balázs, Z Ádám, Z Petkó, B Tímár, Z Szereday, T László, RA Warnke & A Matolcsy
Abstract    Full Article    PDF
Resistance to CD95-mediated apoptosis through constitutive c-FLIP expression in a non-Hodgkin's lymphoma B cell line 2149
M Irisarri, J Plumas, T Bonnefoix, M-C Jacob, C Roucard, M-A Pasquier, J-J Sotto & A Lajmanovich
Abstract    Full Article    PDF
A prospective study of intensive induction therapy with high-dose consolidation in patients with aggressive non-Hodgkin's lymphoma and two or three adverse prognostic factors 2159
C Dumontet, C Thieblemont, D Espinouse, F Bouafia, O Hequet, G Salles & B Coiffier
Abstract    Full Article    PDF

Bio-Technical Methods Section (BTS)
mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method 2166
MG Rots, JC Willey, G Jansen, CH Van Zantwijk, P Noordhuis, JP DeMuth, E Kuiper, AJP Veerman, R Pieters & GJ Peters
Abstract    Full Article    PDF
Detection of hTERT protein by flow cytometry 2176
ASM Ali, R Chopra, J Robertson & NG Testa
Abstract    Full Article    PDF
Extensive characterization of dendritic cells generated in serum-free conditions: regulation of soluble antigen uptake, apoptotic tumor cell phagocytosis, chemotaxis and T cell activation during maturation in vitro 2182
K Tarte, G Fiol, J-F Rossi & B Klein
Abstract    Full Article    PDF

Spotlight on Long-Term Results of Pediatric ALL Clinical Trials from 12 Study Groups World Wide
Long-term results of large prospective trials in childhood acute lymphoblastic leukemia 2193
M Schrappe, B Camitta & C-H Pui
Full Article    PDF
Note from the Editor 2195
N Muller-Bérat, MD
Full Article    PDF

Original Manuscripts
Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) Acute Lymphoblastic Leukemia Studies, 1982–1995 2196
V Conter, M Aricò, MG Valsecchi, G Basso, A Biondi, E Madon, F Mandelli, G Paolucci, A Pession, C Rizzari, R Rondelli, L Zanesco & G Masera for the Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)
Abstract    Full Article    PDF
Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995 2205
M Schrappe, A Reiter, M Zimmermann, J Harbott, W-D Ludwig, G Henze, H Gadner, E Odenwald & H Riehm
Abstract    Full Article    PDF
Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983–1995 2223
PS Gaynon, ME Trigg, NA Heerema, MG Sensel, HN Sather, GD Hammond & WA Bleyer
Abstract    Full Article    PDF
Co-operative study group for childhood acute lymphoblastic leukemia (COALL): long-term follow-up of trials 82, 85, 89 and 92 2234
DO Harms & GE Janka-Schaub on behalf of the COALL Study Group
Abstract    Full Article    PDF
Long-term follow-up of Dutch Childhood Leukemia Study Group (DCLSG) protocols for children with acute lymphoblastic leukemia, 1984–1991 2240
WA Kamps, AJP Veerman, ER van Wering, JF van Weerden, R Slater & A van der Does-van den Berg
Abstract    Full Article    PDF
Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981–1995) 2247
LB Silverman, L Declerck, RD Gelber, V Kimball Dalton, BL Asselin, RD Barr, LA Clavell, CA Hurwitz, A Moghrabi, Y Samson, MA Schorin, JM Lipton, HJ Cohen & SE Sallan
Abstract    Full Article    PDF
Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia: a CLCG-EORTC report 2257
E Vilmer, S Suciu, A Ferster, Y Bertrand, H Cavé, A Thyss, Y Benoit, N Dastugue, M Fournier, G Souillet, A-M Manel, A Robert, B Nelken, F Millot, P Lutz, X Rialland, F Mechinaud, P Boutard, C Behar, J-M Chantraine, E Plouvier, G Laureys, P Brock, A Uyttebroeck, G Margueritte, D Plantaz, L Norton, N Francotte, J Gyselinck, C Waterkeyn, G Solbu, N Philippe & J Otten
Abstract    Full Article    PDF
Improving outcome through two decades in childhood ALL in the Nordic countries: the impact of high-dose methotrexate in the reduction of CNS irradiation 2267
G Gustafsson, K Schmiegelow, E Forestier, N Clausen, A Glomstein, G Jonmundsson, L Mellander, A Mäkipernaa, R Nygaard & UM Saarinen-Pihkala on behalf of the Nordic Society of Pediatric Haematology and Oncology (NOPHO)
Abstract    Full Article    PDF
Long-term results of treatment studies for childhood acute lymphoblastic leukemia: Pediatric Oncology Group studies from 1986–1994 2276
KW Maloney, JJ Shuster, S Murphy, J Pullen & BA Camitta
Abstract    Full Article    PDF
Long-term results of Total Therapy studies 11, 12 and 13A for childhood acute lymphoblastic leukemia at St Jude Children's Research Hospital 2286
C-H Pui, JM Boyett, GK Rivera, ML Hancock, JT Sandlund, RC Ribeiro, JE Rubnitz, FG Behm, SC Raimondi, A Gajjar, B Razzouk, D Campana, LE Kun, MV Relling & WE Evans
Abstract    Full Article    PDF
Long-term follow-up of childhood acute lymphoblastic leukemia in Tokyo Children's Cancer Study Group 1981–1995 2295
M Tsuchida, K Ikuta, R Hanada, T Saito, K Isoyama, K Sugita, Y Toyoda, A Manabe, K Koike, A Kinoshita, M Maeda, K Ishimoto, T Sato, Y Okimoto, T Kaneko, M Kajiwara, M Sotomatsu, Y Hayashi, H Yabe, R Hosoya, Y Hoshi, M Ohira, F Bessho, Y Tsunematsu, I Tsukimoto & S Nakazawa for the Tokyo Children's Cancer Study Group
Abstract    Full Article    PDF
Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980–1997 2307
OB Eden, G Harrison, S Richards, JS Lilleyman, CC Bailey, JM Chessells, IM Hann, FGH Hill & BES Gibson on behalf of the Medical Research Council Childhood Leukaemia Working Party
Abstract    Full Article    PDF

Correspondence
An unusual presentation of a case of T cell angiotropic (intravascular) lymphoma 2321
G Isimbaldi, L Corral, S Songia, MG Valente, S De Bianchi & A Biondi
Full Article    PDF
Intrathecal mitozantrone has to be prohibited 2323
JH Dalle, A Lambilliotte, AS Defachelles, F Mazingue & B Nelken
Full Article    PDF
Is there any genetic susceptibility to acute promyelocytic leukemia? 2324
X Thomas
Full Article    PDF

Author Index
2327
PDF

Keyword Index
2337
PDF
     
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Table of Contents
December 2000, Volume 14, Issue 12

Leukemia

Stockton Press
© Macmillan Publishers Ltd 2000