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Gene Therapy
February 2000, Volume 7, Issue 3
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Gene Therapy
Editorial

Viral transfer technology

Inherited disease

Acquired diseases

Cell based therapy

Editorial
Prospects for gene therapy of diabetes mellitus 181
N Welsh
Full Article    PDF

Viral transfer technology
Efficient gene transfer into human cord blood CD34+ cells and the CD34+CD38- subset using highly purified recombinant adeno-associated viral vector preparations that are free of helper virus and wild-type AAV 183
AC Nathwani, H Hanawa, J Vandergriff, P Kelly, EF Vanin & AW Nienhuis
Abstract    Full Article    PDF
Efficient and sustained transgene expression in human corneal cells mediated by a lentiviral vector 196
X Wang, B Appukuttan, S Ott, R Patel, J Irvine, J Song, J-HC Park, R Smith & JT Stout
Abstract    Full Article    PDF

Inherited disease
Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene 201
PM Wakefield, JM Tinsley, MJA Wood, R Gilbert, G Karpati & KE Davies
Abstract    Full Article    PDF
Glucose regulated production of human insulin in rat hepatocytes 205
PM Thulé, J Liu & LS Phillips
Abstract    Full Article    PDF
An in vitro system for efficiently evaluating gene therapy approaches to hemoglobinopathies 215
RP Howrey, M El-Alfondi, KL Phillips, L Wilson, B Rooney, N Lan, B Sullenger & C Smith
Abstract    Full Article    PDF

Acquired diseases
Secreted human beta-glucuronidase: a novel tool for gene-directed enzyme prodrug therapy 224
D Weyel, H-H Sedlacek, R Müller & S Brüsselbach
Abstract    Full Article    PDF
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins 232
P Boekstegers, G von Degenfeld, W Giehrl, D Heinrich, R Hullin, C Kupatt, G Steinbeck, G Baretton, G Middeler, H Katus & WM Franz
Abstract    Full Article    PDF
Adenovirus-mediated ribozyme targeting of HER-2/neu inhibits in vivo growth of breast cancer cells 241
T Suzuki, B Anderegg, T Ohkawa, A Irie, O Engebraaten, M Halks-Miller, PS Holm, DT Curiel, M Kashani-Sabet & KJ Scanlon
Abstract    Full Article    PDF

Cell based therapy
Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity 249
H Jonuleit, T Tüting, J Steitz, J Brück, A Giesecke, K Steinbrink, J Knop & AH Enk
Abstract    Full Article    PDF
The macrophage – a novel system to deliver gene therapy to pathological hypoxia 255
L Griffiths, K Binley, S Iqball, O Kan, P Maxwell, P Ratcliffe, C Lewis, A Harris, S Kingsman & S Naylor
Abstract    Full Article    PDF
Gene transfer into inflamed glomeruli using macrophages transfected with adenovirus 263
DC Kluth, L-P Erwig, WP Pearce & AJ Rees
Abstract    Full Article    PDF
     
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Table of Contents
February 2000, Volume 7, Issue 3

Gene Therapy

Stockton Press
© Macmillan Publishers Ltd 2000