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Editorial
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Molecular switches for regulating therapeutic genes
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951
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KA Webster
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Perspective
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Coronary angioplasty: an end to early closing?
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954
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WJ Gullick & C Lewanski
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Papers
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Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury
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956
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J Deguchi, T Namba, H Hamada, T Nakaoka, J Abe, O Sato, T Miyata, M Makuuchi, K Kurokawa & Y Takuwa
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| Abstract Full Article PDF
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Improved gene transfer into canine hematopoietic repopulating cells using CD34-enriched marrow cells in combination with a gibbon ape leukemia virus–pseudotype retroviral vector
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966
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H-P Kiem, PA McSweeney, B Bruno, M Goerner, G Buron, J Morris, R Storb & AD Miller
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| Abstract Full Article PDF
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Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
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973
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S Zolotukhin, BJ Byrne, E Mason, I Zolotukhin, M Potter, K Chesnut, C Summerford, RJ Samulski & N Muzyczka
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| Abstract Full Article PDF
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High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap
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986
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JE Conway, CMJ ap Rhys, I Zolotukhin, S Zolotukhin, N Muzyczka, GS Hayward & BJ Byrne
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| Abstract Full Article PDF
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Liposome-mediated NGF gene transfection following neuronal injury: potential therapeutic applications
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994
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LL Zou, L Huang, RL Hayes, C Black, YH Qiu, JR Perez-Polo, W Le, GL Clifton & K Yang
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| Abstract Full Article PDF
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Cell-specific nuclear import of plasmid DNA
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1006
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J Vacik, BS Dean, WE Zimmer & DA Dean
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| Abstract Full Article PDF
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IGF-I gene transfer in thermally injured rats
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1015
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MG Jeschke, RE Barrow, HK Hawkins, K Yang, RL Hayes, BJ Lichtenbelt, JR Perez-Polo & DN Herndon
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| Abstract Full Article PDF
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Differential expression and secretion of alpha 1 anti-trypsin between direct DNA injection and implantation of transfected myoblast
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1021
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G Bou-Gharios, DJ Wells, QL Lu, JE Morgan & T Partridge
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| Abstract Full Article PDF
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Therapeutic efficacy of the thymidine kinase/ganciclovir system on large experimental gliomas: a nuclear magnetic resonance imaging study
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1030
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R Bouali-Benazzouz, M Lainé, JM Vicat, S Boisseau, C Rémy, N Fouilhé, F Thomas, MF Nissou, AL Benabid & F Berger
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| Abstract Full Article PDF
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Development of a modified selective amplifier gene for hematopoietic stem cell gene therapy
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1038
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KM Matsuda, A Kume, Y Ueda, M Urabe, M Hasegawa & K Ozawa
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| Abstract Full Article PDF
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Cellular contaminants of adeno-associated virus vector stocks can enhance transduction
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1045
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L Tenenbaum, M Hamdane, M Pouzet, B Avalosse, A Stathopoulos, F Jurysta, C Rosenbaum, CO Hanemann, M Levivier & T Velu
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| Abstract Full Article PDF
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Induction of apoptosis and G2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection
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1054
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K Brand, R Klocke, A Po ling, D Paul & M Strauss
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| Abstract Full Article PDF
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Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule
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1064
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A Biroccio, D Del Bufalo, A Ricca, C D'Angelo, G D'Orazi, A Sacchi, S Soddu & G Zupi
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| Abstract Full Article PDF
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Induction of complement attack on human cells by Gal(alpha1,3)Gal xenoantigen expression as a gene therapy approach to cancer
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1073
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U Jäger, Y Takeuchi & CD Porter
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| Abstract Full Article PDF
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Retroviral transduction of quiescent haematopoietic cells using a packaging cell line expressing the membrane-bound form of stem cell factor
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1084
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A Sehgal, N Weeratunge & C Casimir
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| Abstract Full Article PDF
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Overexpression of urokinase receptor in mammalian cells following administration of the in vitro transcribed encoding mRNA
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1092
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K Karikó, A Kuo & ES Barnathan
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| Abstract Full Article PDF
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'Autoreplication' of the vector genome in recombinant adenoviral vectors with different E1 region deletions and transgenes
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1101
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U Marienfeld, A Haack, P Thalheimer, S Schneider-Rasp, H-H Brackmann & W Poller
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| Abstract Full Article PDF
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The sCYMV1 hairpin ribozyme: targeting rules and cleavage of heterologous RNA
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1114
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Y Lian, MB De Young, A Siwkowski, A Hampel & J Rappaport
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| Abstract Full Article PDF
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Augmentation of local antitumor immunity in the liver by tumor vaccine modified to secrete murine interleukin 12
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1120
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N Fuji, H Fujiwara, Y Ueda, F Taniguchi, T Yoshimura, T Oka & H Yamagishi
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| Abstract Full Article PDF
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Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis
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1128
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G Wildbaum & N Karin
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| Abstract Full Article PDF
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Ganciclovir-mediated in vivo elimination of myeloid leukemic cells expressing the HSVtk gene induces HSVtk loss variants
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1139
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E Braakman, R Vogels, ACM Martens, J Vermeulen, M Bron, PM Hoogerbrugge, D Valerio & A Hagenbeek
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| Abstract Full Article PDF
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Noradrenaline transporter gene transfer for radiation cell kill by 131I meta-iodobenzylguanidine
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1147
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M Boyd, SH Cunningham, MM Brown, RJ Mairs & TE Wheldon
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| Abstract Full Article PDF
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A novel endothelial cell-based gene therapy platform for the in vivo delivery of apolipoprotein E
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1153
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L Cioffi, FG Sturtz, S Wittmer, B Barut, J Smith-Gbur, V Moore, T Zupancic, B Gilligan, R Auerbach, F Gomez, F Chauvin, M Antczak, D Platika & HR Snodgrass
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| Abstract Full Article PDF
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Lentivirus-mediated Bcl-2 expression in  TC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion
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1160
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P Dupraz, C Rinsch, WF Pralong, E Rolland, R Zufferey, D Trono & B Thorens
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| Abstract Full Article PDF
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Brief Communications
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Retrovirus-mediated WASP gene transfer corrects defective actin polymerization in B cell lines from Wiskott–Aldrich syndrome patients carrying 'null' mutations
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1170
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F Candotti, F Facchetti, L Blanzuoli, DM Stewart, DL Nelson & RM Blaese
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| Abstract Full Article PDF
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Elimination of lysosomal storage in brains of MPS VII mice treated by intrathecal administration of an adeno-associated virus vector
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1175
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SS Elliger, CA Elliger, CP Aguilar, NR Raju & GL Watson
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| Abstract Full Article PDF
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Cationic lipids are essential for gene delivery mediated by intravenous administration of lipoplexes
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1179
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LG Barron, LS Uyechi & FC Szoka Jr
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| Abstract Full Article PDF
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Tissue-selective expression of dominant-negative proteins for the regulation of vascular smooth muscle cell proliferation
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1184
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JF Schmitt, M-C Keogh, U Dennehy, D Chen, F Lupu, K Weston, D Taylor, VV Kakkar & NR Lemoine
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| Abstract Full Article PDF
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Insulation of a conditionally expressed transgene in an adenoviral vector
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1192
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G Vassaux, HC Hurst & NR Lemoine
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| Abstract Full Article PDF
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