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Original Articles
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Cell cycle start from quiescence controlled by tyrosine phosphorylation of Cdk4
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565
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Shigeki Jinno, Shih-Chieh Hung & Hiroto Okayama
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| Abstract Full Article PDF
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A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2
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573
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Veronika Sexl, J Alan Diehl, Charles J Sherr, Richard Ashmun, David Beach & Martine F Roussel
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| Abstract Full Article PDF
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Inhibition of RNA polymerase II as a trigger for the p53 response
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583
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Mats Ljungman, Fenfen Zhang, Feng Chen, Andrew J Rainbow & Bruce C McKay
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| Abstract Full Article PDF
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Association with E2F-1 governs intracellular trafficking and polyubiquitination of DP-1
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593
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Junji Magae, Sharon Illenye, Young-Chae Chang, Youji Mitsui & Nicholas H Heintz
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| Abstract Full Article PDF
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The bovine papillomavirus type 1 E6 oncoprotein sensitizes cells to tumor necrosis factor alpha-induced apoptosis
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607
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Lisa Rapp, Yun Liu, Yihui Hong, Elliot J Androphy & Jason J Chen
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| Abstract Full Article PDF
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Detection of mutations by automated fluorescence/RNA-based dideoxy fingerprinting (ARddF)
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617
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D Martincic, MJ Koury, K Gale & JA Whitlock
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| Abstract Full Article PDF
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Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4
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623
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Guofang Qiu, Mansoor Ahmed, Stephen F Sells, Mohammed Mohiuddin, Michael H Weinstein & Vivek M Rangnekar
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| Abstract Full Article PDF
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Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia
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633
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Jeff L Hummel, Richard A Wells, Ian D Dubé, Jonathan D Licht & Suzanne Kamel-Reid
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| Abstract Full Article PDF
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Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
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643
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Ignacio I Wistuba, Carmen Behrens, Sara Milchgrub, David Bryant, Jaclyn Hung, John D Minna & Adi F Gazdar
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| Abstract Full Article PDF
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Ectopic expression of pRb2/p130 suppresses the tumorigenicity of the c-erbB-2-overexpressing SKOV3 tumor cell line
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651
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Serenella M Pupa, Candace M Howard, Anna M Invernizzi, Roberta De Vecchi, Cristiana Giani, Pier Paolo Claudio, Maria I Colnaghi, Antonio Giordano & Sylvie Ménard
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| Abstract Full Article PDF
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Two novel regions of interstitial deletion on chromosome 8p in colorectal cancer
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657
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Shaheen A Chughtai, Malcolm C Crundwell, Neil RJ Cruickshank, Edwina Affie, Sue Armstrong, Margaret A Knowles, Lyndsay A Takle, Michael Kuo, Neil Khan, Stewart MA Phillips, John P Neoptolemos & Dion G Morton
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| Abstract Full Article PDF
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Both AP-1 and Cbfa1-like factors are required for the induction of interstitial collagenase by parathyroid hormone
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667
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D Porte, J Tuckermann, M Becker, B Baumann, S Teurich, T Higgins, MJ Owen, M Schorpp-Kistner & P Angel
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| Abstract Full Article PDF
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Rapid dephosphorylation of p107 following UV irradiation
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679
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P Mathijs Voorhoeve, Roger J Watson, Peter G Farlie, René Bernards & Eric W-F Lam
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| Abstract Full Article PDF
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The product of the cph oncogene is a truncated, nucleotide-binding protein that enhances cellular survival to stress
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689
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Juan A Velasco, Matias A Avila & Vicente Notario
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| Abstract Full Article PDF
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Growth stimulation of murine fibroblasts by TGF- 1 depends on the expression of a functional p53 protein
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703
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Fatima Dkhissi, Stéphane Raynal, Pierre Jullien & David A Lawrence
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| Abstract Full Article PDF
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Bcl-2 interferes with the execution phase, but not upstream events, in glucocorticoid-induced leukemia apoptosis
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713
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Bernd L Hartmann, Stephan Geley, Markus Löffler, Rosa Hattmannstorfer, Elisabeth MC Strasser-Wozak, Bernhard Auer & Reinhard Kofler
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| Abstract Full Article PDF
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Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocation
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721
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Hiroshi Kanoe, Tomitaka Nakayama, Taisuke Hosaka, Hiroshi Murakami, Hiroshi Yamamoto, Yasuaki Nakashima, Tadao Tsuboyama, Takashi Nakamura, David Ron, Masao S Sasaki & Junya Toguchida
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| Abstract Full Article PDF
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Augmentation of a humanized Anti-HER2 mAb 4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor mAb C225
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731
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Dingwei Ye, John Mendelsohn & Zhen Fan
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| Abstract Full Article PDF
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The expression of P-glycoprotein is causally related to a less aggressive phenotype in human osteosarcoma cells
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739
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Katia Scotlandi, Maria Cristina Manara, Massimo Serra, Stefania Benini, Daniela Maurici, Antonella Caputo, Carla De Giovanni, Pier-Luigi Lollini, Patrizia Nanni, Piero Picci, Mario Campanacci & Nicola Baldini
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Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF- B
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747
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Andreas Dumont, Steffen P Hehner, Thomas G Hofmann, Marius Ueffing, Wulf Dröge & M Lienhard Schmitz
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APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis
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759
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Masahiro Yokouchi, Toru Wakioka, Hiroshi Sakamoto, Hideo Yasukawa, Satoshi Ohtsuka, Atsuo Sasaki, Motoaki Ohtsubo, Mindaugas Valius, Akio Inoue, Setsuro Komiya & Akihiko Yoshimura
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| Abstract Full Article PDF
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Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase 
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769
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Claudia Kühn, Friedemann Müller, Christian Melle, Heinz-Peter Nasheuer, Friedemann Janus, Wolfgang Deppert & Frank Grosse
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Distinct chromosomal alterations associated with TP53 status of LoVo cells under PALA selective pressure: a parallel with cytogenetic pathways of colorectal cancers
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775
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Priscilla Soulie, Marie-France Poupon, Yorghos Remvikos, Bernard Dutrillaux & Martine Muleris
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| Abstract Full Article PDF
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Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas
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783
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Jay S Wunder, Kolja Eppert, Sarah R Burrow, Nalan Gogkoz, Robert S Bell & Irene L Andrulis
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| Abstract Full Article PDF
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High frequency of p16INK4A gene alterations in hepatocellular carcinoma
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789
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Choong Tsek Liew, Hiu-Ming Li, Kwok-Wai Lo, Chon Kar Leow, John YH Chan, Lin Yee Hin, Wan Yee Lau, Paul Bo San Lai, Boon Kian Lim, Jin Huang, Wai Tong Leung, Shan Wu & Joseph Chuen Kwun Lee
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Mechanism of activation of Pak1 kinase by membrane localization
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797
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Wange Lu & Bruce J Mayer
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Reduced growth rate and transformation phenotype of the prostate cancer cells by an interferon-inducible protein, p202
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807
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Duen-Hwa Yan, Yong Wen, Bill Spohn, Divaker Choubey, Jordan U Gutterman & Mien-Chie Hung
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| Abstract Full Article PDF
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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
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813
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Rika Hoshino, Yuji Chatani, Takao Yamori, Takashi Tsuruo, Hiroya Oka, Osamu Yoshida, Yutaka Shimada, Shigeki Ari-i, Hiromi Wada, Jiro Fujimoto & Michiaki Kohno
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Short Reports
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Localization of a novel tumor suppressor gene associated with human oral cancer on chromosome 4q25
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823
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Xiao-Li Wang, Katsuhiro Uzawa, Fabiana L Imai & Hideki Tanzawa
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| Abstract Full Article PDF
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Differential gene expression in neoplastic and human papillomavirus-immortalized oral keratinocytes
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827
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Osvaldo Rey, Marcel A Baluda & No-Hee Park
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| Abstract Full Article PDF
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A frequent activated smoothened mutation in sporadic basal cell carcinomas
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833
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Ching-Wan Lam, Jingwu Xie, Ka-Fai To, Ho-Keung Ng, Kam-Cheong Lee, Nancy Wah-Fun Yuen, Pak-Leong Lim, Lisa Yuen-Shan Chan, Sui-Fan Tong & Frank McCormick
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| Abstract Full Article PDF
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Linkage between melanocytic tumor development and early burst of Ret protein expression for tolerance induction in metallothionein-I/ret transgenic mouse lines
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837
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Masashi Kato, Wei Liu, Anwarul A Akhand, Yan Dai, Masaharu Ohbayashi, Toyonori Tuzuki, Haruhiko Suzuki, Ken-Ichi Isobe, Masahide Takahashi & Izumi Nakashima
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| Abstract Full Article PDF
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Different regulation of c-Myc- and E2F-1-induced apoptosis during the ongoing cell cycle
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843
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Markus Hengstschläger, Gabriele Hölzl & Elke Hengstschläger-Ottnad
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