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Leukemia
Normal and Malignant Hemopoiesis

June 1999, Volume 13, Issue 6
Table of Contents

Journal Home
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Mini-Review

The biological basis for the attenuation of mucositis: the example of interleukin-11 831
S Sonis, L Edwards & C Lucey
Abstract    Full Article (PDF)

Open Forum

Guidelines for the characterization and publication of human malignant hematopoietic cell lines 835
HG Drexler & Y Matsuo
Abstract    Full Article (PDF)

Original Manuscripts

Therapy
Multicenter randomized phase II trial of idarubicin vs mitoxantrone, combined with VP-16 and cytarabine for induction/consolidation therapy, followed by a feasibility study of autologous peripheral blood stem cell transplantation in elderly patients with acute myeloid leukemia 843
E Archimbaud, U Jehn, X Thomas, F De Cataldo, G Fillet, A Belhabri, P-Y Peaud, C Martin, S Amadori & R Willemze
Abstract    Full Article (PDF)

Treatment of newly diagnosed AML, RAEB-t or RAEB with lisofylline or placebo in addition to chemotherapy 850
EH Estey, PF Thall, P Reed, H Kantarjian, M Beran, S Pierce & MJ Keating
Abstract    Full Article (PDF)

Perspectives in Therapy
Therapeutic targeting of Src-kinase Lyn in myeloid leukemic cell growth 855
V Roginskaya, S Zuo, E Caudell, G Nambudiri, AJ Kraker & SJ Corey
Abstract    Full Article (PDF)

APL
Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia 862
M-J Mozziconacci, C Liberatore, F Grignani, D Sainty, PG Pelicci, F Birg & M Lafage-Pochitaloff
Abstract    Full Article (PDF)

ALL and Cytogenetics
Deletions and losses in chromosomes 5 or 7 in adult acute lymphocytic leukemia: incidence, associations and implications 869
BS Dabaja, S Faderl, D Thomas, J Cortes, S O’Brien, F Nasr, S Pierce, K Hayes, A Glassman, M Keating & HM Kantarjian
Abstract    Full Article (PDF)

Molecular Cytogenetics
B cell prolymphocytic leukaemia (B-PLL) with complex karyotype and concurrent abnormalities of the p53 and c-MYC gene 873
D Lens, LJA Coignet, V Brito-Babapulle, CSP Lima, E Matutes, MJS Dyer & D Catovsky
Abstract    Full Article (PDF)

Tumor Supressor Genes and Methylation
Cancer-specific region of hypermethylation identified within the HIC1 putative tumour suppressor gene in acute myeloid leukaemia 877
JR Melki, PC Vincent & SJ Clark
Abstract    Full Article (PDF)

p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in childhood acute lymphoblastic leukemia with 11q23 translocation 884
M Nakamura, K Sugita, T Inukai, K Goi, K Iijima, T Tezuka, S Kojika, K Shiraishi, N Miyamoto, N Karakida, K Kagami, T O-Koyama, T Mori & S Nakazawa
Abstract    Full Article (PDF)

Gene Expression in MDS and AML
WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia 891
P Patmasiriwat, G Fraizer, H Kantarjian & GF Saunders
Abstract    Full Article (PDF)

Apoptosis
Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds 901
L Tentori, M Turriziani, D Franco, A Serafino, L Levati, R Roy, E Bonmassar & G Graziani
Abstract    Full Article (PDF)

Sensitivity and Resistance to Therapy
Methylation analysis of the human multidrug resistance 1 gene in normal and leukemic hematopoietic cells 910
KB Fryxell, SB McGee, DK Simoneaux, CL Willman & MM Cornwell
Abstract    Full Article (PDF)

Potentiation of antitumor effects of cyclophosphamide derivatives in B-chronic lymphocytic leukemia cells by 2-chloro-2'-deoxyadenosine 918
E Van Den Neste, F Bontemps, A Delacauw, S Cardoen, I Louviaux, JM Scheiff, E Gillis, P Leveugle, V Deneys, A Ferrant & G Van den Berghe
Abstract    Full Article (PDF)

Growth Factors, Cytokines and Cell Signalling
Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1 926
D Metcalf, WS Alexander, AG Elefanty, NA Nicola, DJ Hilton, R Starr, S Mifsud & L Di Rago
Abstract    Full Article (PDF)

Megakaryocytic Differentiation
Megakaryocytic differentiation of human progenitor cells is negatively influenced by direct contact with stroma 935
S Zweegman, MA Veenhof, N Debili, GJ Schuurhuis, PC Huijgens & AM Dräger
Abstract    Full Article (PDF)

Stem Cell Harvests in CML
Analysis of CD34 populations in mobilised peripheral blood stem cell harvests and in bone marrow by fluorescent in situ hybridisation for the bcr/abl gene fusion in patients with chronic granulocytic leukaemia 944
JAE Irving, A Lennard, N Storey, J Conn, J Dunn, K Oliver, SJ Proctor & AM Dickinson
Abstract    Full Article (PDF)

Lymphoma
Intensive sequential chemotherapy (ISC 95) with growth factors and blood stem cell support in high-intermediate and high-risk (IPI 2 and IPI 3) aggressive non-Hodgkin’s lymphoma: an oligocentric report on 42 patients 950
R Bouabdallah, A-M Stoppa, J-F Rossi, G Lepeu, D Coso, L Xerri, P Ladaique, C Chabannon, D Blaise, V-J Bardou, C Alzieu, J-A Gastaut & D Maraninchi
Abstract    Full Article (PDF)

Biotechnical Methods Section (BTS)
Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a ‘real time’ quantitative RT-PCR assay 957
C Preudhomme, F Révillion, A Merlat, L Hornez, C Roumier, N Duflos-Grardel, JP Jouet, A Cosson, JP Peyrat & P Fenaux
Abstract    Full Article (PDF)

Detection of T cell receptor beta (TCRB) gene rearrangement patterns in T cell malignancies by Southern blot analysis 965
AW Langerak, ILM Wolvers-Tettero & JJM van Dongen
Abstract    Full Article (PDF)

Brief Communication

Molecular characterization of a complex chromosomal translocation breakpoint t(10;14) including the HOX11 oncogene locus 975
PD Salvati, PM Watt, WR Thomas & UR Kees
Abstract    Full Article (PDF)

Correspondence

Low-dose cytarabine (LD-AraC) plus recombinant human granulocyte colony-stimulating factor (rhG-CSF) for myelodysplastic syndromes (MDS) 980
A Kikuchi, H Ohashi, R Hanada & K Yamamoto
Full Article (PDF)

Are we ready to curtail testing TEL/AML1 fusion? 981
O Hrus caronák, J Trka, J Zuna, J Bartu ringn caronková, J Starý for Pediatric Hematology Working Group in the Czech Republic
Full Article (PDF)

Reply
Reply: Immunophenotypic prediction of TEL-AML1 rearrangement in childhood ALL 983
MJ Borowitz, J Rubnitz, M Nash, DJ Pullen, B Camitta for the Pediatric Oncology Group
Full Article (PDF)

© Macmillan Publishers Ltd 1999

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, environmental epidemiology, gene therapy, hematology, human and experimental toxicology, exposure analysis, human hypertension, impotence research, industrial microbiology, industrial health, information systems, leukemia, lupus, microcirculation, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, occupational medicine, oncology, oncology pharmacy practice, operations research, optometry and ophthalmology, oral diseases, orthopedics, paraplegia, perinatology, pharmacology, psychiatry, public health, spinal injury and disease.