Gene Therapy

April 1998, Volume 5, Issue 4
Table of Contents

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News and Comments

427
Full Article (PDF)

Editorial

Impact of a new generation of gene transfer markers on gene therapy 429
B Fehse, Z Li, UM Schade, A Uhde & AR Zander
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Papers

Effects of macrophage depletion and anti-CD40 ligand on transgene expression and redosing with recombinant adenovirus 431
CS Stein, JL Pemberton, N van Rooijen & BL Davidson
Abstract    Full Article (PDF)
Selective astrocytic transgene expression in vitro and in vivo from the GFAP promoter in a HSV RL1 null mutant vector - potential glioblastoma targeting 440
EA McKie, DI Graham & SM Brown
Abstract    Full Article (PDF)
Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration 451
MM van der Eb, SJ Cramer, Y Vergouwe, FHE Schagen, JHJM van Krieken, AJ van der Eb, IHM Borel Rinkes, CJH van de Velde & RC Hoeben
Abstract    Full Article (PDF)
Persistent gene expression in rat liver in vivo by repetitive transfections using HVJ-liposome 459
T Hirano, J Fujimoto, T Ueki, H Yamamoto, T Iwasaki, R Morisita, Y Sawa, Y Kaneda, H Takahashi & E Okamoto
Abstract    Full Article (PDF)
Adenovirus vectors for gene transduction into mobilized blood CD34+ cells 465
M Bregni, S Shammah, F Malaffo, M Di Nicola, M Milanesi, M Magni, P Matteucci, F Ravagnani, CT Jordan, S Siena & AM Gianni
Abstract    Full Article (PDF)
Complete correction of acid alpha-glucosidase deficiency in Pompe disease fibroblasts in vitro, and lysosomally targeted expression in neonatal rat cardiac and skeletal muscle 473
DF Pauly, DC Johns, LA Matelis, JH Lawrence, BJ Byrne & PD Kessler
Abstract    Full Article (PDF)
Vaccination with IL-12 gene-modified autologous melanoma cells: preclinical results and a first clinical phase I study 481
Y Sun, K Jurgovsky, P Möller, S Alijagic, T Dorbic, J Georgieva, B Wittig & D Schadendorf
Abstract    Full Article (PDF)
Drug inducible transgene expression in brain using a herpes simplex virus vector 491
T Oligino, PL Poliani, Y Wang, SY Tsai, BW O’Malley, DJ Fink & JC Glorioso
Abstract    Full Article (PDF)
Major effects of TPO delivered by a single injection of a recombinant adenovirus on prevention of septicemia and anemia associated with myelosuppression in mice: risk of sustained expression inducing myelofibrosis due to immunosuppression 497
MA Abina, M Tulliez, C Lacout, N Debili, J-L Villeval, F Pflumio, F Wendling, W Vainchenker & H Haddada
Abstract    Full Article (PDF)
Regional ‘pro-drug’ gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma 507
N Topf, S Worgall, NR Hackett & RG Crystal
Abstract    Full Article (PDF)
Myosin regulatory elements as vectors for gene transfer by intramuscular injection 514
M Skarli, A Kiri, G Vrbova, CA Lee & G Goldspink
Abstract    Full Article (PDF)
A chimeric fusion protein containing transforming growth factor-alpha mediates gene transfer via binding to the EGF receptor 521
J Fominaya, C Uherek & W Wels
Abstract    Full Article (PDF)
Baculovirus-mediated gene transfer in the presence of human serum or blood facilitated by inhibition of the complement system 531
C Hofmann & M Strauss
Abstract    Full Article (PDF)
Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands 537
X He, CM Goldsmith, Y Marmary, RB Wellner, AF Parlow, LK Nieman & BJ Baum
Abstract    Full Article (PDF)
Lipofection of cultured mouse muscle cells: a direct comparison of Lipofectamine and DOSPER 542
E Dodds, MG Dunckley, K Naujoks, U Michaelis & G Dickson
Abstract    Full Article (PDF)

Brief Communications

Retroviral gene transfer to the liver in vivo during tri-iodothyronine induced hyperplasia 552
SJ Forbes, M Themis, MR Alison, C Selden, C Coutelle & HJF Hodgson
Abstract    Full Article (PDF)
Rapid analysis and efficient selection of human transduced primitive hematopoietic cells using the humanized S65T green fluorescent protein 556
F Mazurier, F Moreau-Gaudry, V Maguer-Satta, S Salesse, V Pigeonnier-Lagarde, C Ged, F Belloc, F Lacombe, FX Mahon, J Reiffers & H de Verneuil
Abstract    Full Article (PDF)
FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors 563
AT Larregina, AE Morelli, RA Dewey, MG Castro, A Fontana & PR Lowenstein
Abstract    Full Article (PDF)

Corrigenda

Safety of a single aerosol administration of escalating doses of the cationic lipid GL-67/DOPE/DMPE-PEG5000 formulation to the lungs of normal volunteers 569
SL Chadwick, HD Kingston, M Stern, RM Cook, BJ O’Connor, M Lukasson, RP Balfour, M Rosenberg, SH Cheng, AE Smith, DP Meeker, DM Geddes & EWFW Alton
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Intracellular inhibition of HIV-1 replication using a dual protein- and RNA-based strategy 570
L-X Duan, M Zhu, I Ozaki, DL Wei & RJ Pomerantz
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© Macmillan Publishers Ltd 1998

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, gene therapy, haematology, human and experimental toxicology, human hypertension, impotence research, industrial microbiology, information systems, leukemia, lupus, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, oncology, operations research, optometry and ophthalmology, oral diseases, orthopaedics, paraplegia, pharmacology, psychiatry, public health, spinal injury and disease.